الدكتورة حنين ذويب تُشارك في نشر دراسة جديدة بعنوان " بروتوكول لإنتاج نموذج فئران لمرض السكري ما قبل السمنة باستخدام نظام غذائي خفيف عالي السعرات الحرارية"

ملخص البحث

Metabolic disease complications pose a significant health risk due to their early development, making their diagnosis and radical therapy a considerable challenge. Here, we present a protocol for producing a rat model of non-obese prediabetes characterized by hyperinsulinemia, normoglycemia, and normal body weight. We describe steps for inducing the model in Sprague-Dawley (SD) male and ovariectomized female rats by free feeding on a mild hypercaloric diet. This protocol offers a potential model of metabolically unhealthy lean individuals.

كيفية الاستشهاد للبحث:

Dwaib, H. S., & El-Yazbi, A. F. (2024). Protocol for producing a rat model of non-obese prediabetes using a mild hypercaloric diet approach. STAR protocols, 5(3), 103276.‏

رابط البحث

https://www.sciencedirect.com/science/article/pii/S2666166724004416